Usual adult dose: Analgesic or Antidysmenorrheal: 500 mg, 3 times a day initially, followed by 250 mg every six hours as needed.
Note: It is recommended that mefenamic acid be used for no longer than 7 days at a time.
Usual pediatric dose: Children up to 14 years of age: Safety and efficacy have not been established.
Additional dosing information: It is recommended that mefenamic acid therapy be discontinued promptly if diarrhea or a skin rash develops. Patients who develop diarrhea during mefenamic acid therapy are usually unable to tolerate the drug there after.